Senna-alexandrina abuse

933-940 Lemos Senna LAJP 1824:Lemos Senna

Candidate DNA Barcode Tags Combined With High Resolution Melting (Bar-HRM) Curve Analysis for Authentication of Senna alexandrina Mill. With Validation in Crude Drugs

Senna alexandrina (Fabaceae) is a globally recognized medicinal plant for its laxative properties as well as the only source of sennosides, and is highly exported bulk herb from India. Its major procurement is exclusively from limited cultivation, which leads to risks of deliberate or unintended adulteration. The market raw materials are in powdered or finished product form, which lead to diffi...

HPTLC DENSITOMETRIC QUANTIFICATION OF SENNOSIDES FROM Cassia angustifolia

The use of medicinal herbs to relieve and treat diseases is increasing because of their mild features and few side effects (Basgel and Erdemoglu, 2006). These plants are unlicensed and freely available, however, and there is no requirement to demonstrate efficacy, safety or quality (Ernst, 1998). Cassia angustifolia Vahl (Family: Caesalpinaceae), popularly known as senna, is a valuable plant dr...

Laxative activities of Cassia sieberiana and Senna obtusifolia.

BACKGROUND The root and stem bark of Cassia sieberiana DC. (Caesalpiniaceae) and the root of Senna obtusifolia (Linn) Irwin and Barneby (Caesalpiniaceae), used for constipation in Nigeria, were assayed for laxative properties in male albino rats using the official senna leaf (Senna alexandrina Mill. family Caesalpiniaceae) as the reference standard. This is with a view to finding alternative la...

A Modified Method for Isolation of Rhein from Senna

A simple and efficient method for the isolation of rhein from Cassia angustifolia (senna) leaves is described in which the hydrolysis of the sennosides and extraction of the hydrolysis products (free anthraquinones) is carried out in one step. Further isolation of rhein is achieved from the anthraquinone mixture. This method reduces the number of steps required for isolation of rhein as compare...